Acyclovir and Zovirax

Herpes is a common and highly contagious infection typically marked by clusters of small, painful blisters on the skin. Two types of viruses cause it – HSV-1 and HSV-2. Despite being so prevalent, herpes remains incurable, highlighting the need for effective treatments to manage symptoms and prevent outbreaks.

One such treatment is Acyclovir, also marketed under the brand name Zovirax. This antiviral medication has proven instrumental in helping those affected by herpes manage their condition effectively. This article aims to shed light on Acyclovir and Zovirax as effective treatments for herpes, discussing their usage, effectiveness, and essential role in herpes management. Whether you’re newly diagnosed, seeking better control of your symptoms, or want to understand more about this common condition, this article aims to provide the information you need.

Understanding Herpes

Herpes is an STD caused by Oral herpes (HSV-1) and genital herpes (HSV-2). 

Herpes is spread via direct contact with the virus, usually during oral, vaginal, or anal sex. The virus can also be spread from an infected mother to a baby during birth. It’s important to note that herpes can be transmitted without visible symptoms.

The impact of herpes on individuals varies significantly. Some people may have mild or no symptoms, while others experience painful sores, fever, body aches, and swollen lymph nodes during outbreaks. Recurrent outbreaks are common, especially in the first year of infection.

Psychologically, a herpes diagnosis can lead to feelings of shame, frustration, and distress. It can affect relationships and cause significant emotional pain.

Early detection and treatment of herpes are crucial. While there’s no cure for herpes, antiviral medications like Acyclovir and Zovirax can help manage symptoms, reduce the amount of outbreaks, and reduce the risk of spreading the virus to others. Regular testing is recommended, especially for those sexually active with multiple partners, as it helps in early detection and management of the disease.


Zovirax and Acyclovir 

Acyclovir, marketed by the brand name Zovirax, is an antiviral medication used primarily to treat outbreaks of herpes simplex virus infections, including cold sores, genital herpes, and shingles (herpes zoster). It is also prescribed for chickenpox in children.

Chemically, Acyclovir is a synthetic purine nucleoside analog. It comprises a guanine (“G”) base attached to the acyclic sugar alcohol acycloguanosine.

Acyclovir/Zovirax works by inhibiting the replication of viral DNA needed for the virus to multiply and spread. When the virus tries to replicate, Acyclovir is incorporated into its DNA, leading to premature chain termination. This stops the growth of the virus and reduces the severity of outbreaks.

It’s important to note that Acyclovir/Zovirax can manage symptoms and reduce outbreaks. Acyclovir does not cure herpes or prevent the transmission of the virus to others.

The Role of Acyclovir/Zovirax in Treating Herpes

Acyclovir/Zovirax plays a crucial role in managing herpes simplex virus infections. The medication is designed to slow the growth and spread of the herpes virus, enabling the body to fight off the infection. It reduces the severity and duration of outbreaks, helping sores heal faster, preventing new sores from forming, and decreasing pain/itching. Additionally, it helps reduce how long pain remains after the sores heal.

In cases of recurrent genital herpes, Acyclovir/Zovirax can be taken daily as suppressive therapy to reduce the frequency of outbreaks and decrease the risk of transmitting the virus to partners. For patients with frequent outbreaks (6 or more per year), suppressive therapy reduces outbreaks by 70%-80%.

A study published in the Journal of Clinical Microbiology found that topical Acyclovir effectively treated initial and recurrent genital herpes, with most patients experiencing full recovery within ten days. Another study in The Lancet showed that Acyclovir reduced the duration of viral shedding (when the virus is active and potentially transmissible) and promoted the healing of lesions.

However, while Acyclovir/Zovirax is effective in managing genital and oral herpes symptoms and reducing outbreaks, it does not remedy herpes or stop the transmission of the virus to others. It’s also important to note that individual responses to the medication can vary, and what works best will depend on the individual’s health status, the severity of their symptoms, and their healthcare provider’s recommendations.

How to Use Acyclovir/Zovirax

Acyclovir/Zovirax comes in various forms, including tablets, capsules, liquid suspension, and topical cream. The method of use and dosage depends on the condition and the patient’s response to treatment.

Acyclovir is typically taken 2 to 5 times daily, with or without food for oral use. Maintaining adequate hydration while taking Acyclovir is crucial to prevent kidney problems.

When using Acyclovir topical cream, a thin layer should be applied to the affected area(s) as directed by your healthcare provider, usually five times daily. It’s essential not to use the cream on unaffected skin or inside the mouth, nose, or eyes.

Regardless of the form, starting Acyclovir immediately after the first signs of an outbreak (e.g., tingling, burning, blisters) is vital for maximum effectiveness.

Common side effects have been known to include vomiting, diarrhea, nausea, and headache. In rare cases, Acyclovir may cause serious kidney problems or a potentially life-threatening allergic reaction. If you notice unusual tiredness, changes in the amount of urine, rash, itching/swelling (especially of the face/tongue/throat), or severe dizziness, seek medical attention promptly.

Always follow your doctor’s instructions regarding dosage and frequency, and do not stop taking the medication without your doctor’s approval, even if your symptoms disappear.

acyclovir dosage for herpes

Acyclovir Dosage for Herpes

To remedy genital herpes, grown-ups and youths 12 years and older typically take 200 milligrams (mg) five times a day for ten days. Some sources suggest an initial treatment of 200 mg every four hours while awake (five times daily) for 10 days or 400 mg every eight hours for 7-10 days. An intermittent treatment for recurrence might involve taking 200 mg as needed.

It’s also worth noting that alternative dosages exist, such as Acyclovir 400 mg orally three times per day for five days. In some cases, a dose of Acyclovir 1 g twice daily for three days has been found effective. For shingles, genital herpes, or chickenpox, the typical initial dosage is 200 mg every four hours, five times daily, for 10 days.

Sometimes, a single “stat” 800-mg dose of Acyclovir taken at the first sensory signs for either oral or genital herpes simplex can prevent lesions from developing. Acyclovir can help treat herpes zoster.

The Importance of Regular Herpes Testing with

STD Testing is an essential aspect of maintaining sexual health, especially for individuals who are sexually active or have had a history of herpes infections. This remains true even for those using antiviral treatments like Acyclovir/Zovirax. Herpes can be an asymptomatic STD.

Testing for herpes simplex virus can help identify if an infection is present, even without symptoms. Many people with herpes do not exhibit any noticeable signs or symptoms, or they mistake their symptoms for something else. Regular testing allows for early detection, leading to rapid remedy and decreasing the risk of complications and transmission to others.

Herpes tests typically involve either a viral culture or a blood test. The former requires a sample from a sore, while the latter detects antibodies against the virus in the blood. It’s important to note that it takes time for the body to develop these antibodies, so getting tested too soon after exposure may yield inaccurate results.

Reputable STD testing clinics like offer confidential, private testing for sexually transmitted diseases, including herpes. They provide quick and accurate results, usually within 1-2 days. Their services are designed to be user-friendly and respectful of privacy, ensuring that your personal information and results are kept confidential.

Regular herpes testing and the responsible use of medications like Acyclovir/Zovirax are critical to managing herpes effectively. It encourages honest communication with partners about STI risks and safer sex practices, contributing to overall public health efforts to control.

Acyclovir Herpes

Acyclovir/Zovirax has proven to be a powerful ally in the fight against herpes simplex virus infections. This antiviral medication works by slowing the spread of the herpes virus in the body, helping to alleviate the pain, discomfort, and appearance of sores associated with outbreaks. While it won’t cure herpes – a reality we must face when dealing with this persistent virus – it plays a significant role in managing symptoms, reducing the severity and frequency of outbreaks, and improving the quality of life for those affected.

In addition to using Acyclovir/Zovirax, regular herpes testing is of paramount importance. Regular testing allows for early detection of the herpes virus, even when no symptoms are present. Early detection can lead to prompt treatment initiation, critical for managing the condition effectively.

Reputable STD testing clinics offer private testing services, ensuring patients can comfortably and conveniently get tested. These services are crucial in our collective effort to control the spread of STIs and promote sexual health awareness.

In summary, while treatments like Acyclovir/Zovirax are essential tools in managing herpes, they must be combined with regular testing and early treatment initiation for optimal results. It’s a holistic approach focusing on symptom management, prevention, and education, contributing to a healthier society.

Medically Reviewed by on September 11, 2023

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